Document Type

Article

Keywords

3-Bromo-6-chloro-8-quinolinol, 6-Bromo-3-chloro-8-quinolinol, 3-Bromo-6,8-dihydroxyquinoline, 3-Chloro-6,8-dihydroxyquinoline, Fungitoxicity

Disciplines

Biochemistry

Abstract

3-Bromo-6-chloro- and 6-bromo-3-chloro-8-nitro, -8-amino-, and -8-hydroxyquinolines along with 3-bromo- and 3-chloroquinolin-6,8-diols were prepared and tested for antifungal activity against six fungi (Aspergillus niger, A. oryzae, Myrothecium verrucaria, Trichoderma viride, Mucor cirinelloides, Trichophyton mentagrophytes) in Sabouraud dextrose broth. Compounds with chlorine in the 3 position were generally more fungitoxic than the corresponding analogues with bromine. 6-Bromo-3-chloro-8-quinolinol inhibited four fungi at levels below 1 μg/ml and A. niger and M. cirinelloides at 2 μg/ml each

Article Number

1080

Publication Date

1996

Comments

Monatshefte für Chemie 127:331-337. http://0-dx.doi.org.library.simmons.edu/10.1007/BF00813800

Included in

Biochemistry Commons

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