Document Type

Article

Keywords

Antifungal activity, Halophenols, Halonitrophenols

Disciplines

Biochemistry

Abstract

Thirty one compounds (phenol; its 12 possible monohalo analogues; 18 nitrophenols (2- and 4-nitrophenols, 4-, 5-, and 6-halo-2-nitrophenols, 3-halo-4-nitrophenols)) were tested for antifungal activity against six fungi (A. niger, A. oryzae, M. verrucaria, T. viride, M. cirinelloides, and T. mentagrophytes) in Sabouraud dextrose broth. The two most fungitoxic compounds of those studied were 5-fluoro- and 5-iodo-2-nitrophenols which inhibited all the fungi at concentrations under 10 μg/ml. 6-Iodo-2-nitrophenol inhibited five fungi at a concentration below 10 μg/ml and M. cirinelloides at 10- 100 μg/ ml

Article Number

1057

Publication Date

1995

Comments

Monatshefte für chemie 126:1161-1166. http://0-dx.doi.org.library.simmons.edu/10.1007/BF00811385

Included in

Biochemistry Commons

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