Document Type

Article

Keywords

Trichloro-8-quinolinols, Tribromo-8-quinolinols, Tetrachloro-8-quinolinols, Tetrabromo-8-quinolinols, Antifungal activity

Disciplines

Biochemistry

Abstract

3,5,6-, 3,5,7-, 4,5,7-, and 5,6,7-trichloro- and -tribromo-8-quinolinols as well as 3,5,6,7- tetrachloro- and -tetrabromo-8-quinolinols were prepared and tested against six fungi (Aspergillus niger, Aspergillus oryzae, Myrothecium verrucaria, Trichoderma viride, Mucor cirinelloides, and Trichophyton mentagrophytes) in Sabouraud dextrose broth. The compounds strongly inhibit five fungi but not M. cirinelloides. They are less active than the related dichloro-8-quinolinols which is attributed to steric hindrance

Article Number

1052

Publication Date

2001

Comments

Monatshefte für chemie 132:1075-1080. http://0-dx.doi.org.library.simmons.edu/10.1007/s007060170048

Included in

Biochemistry Commons

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